Advanced Biomimetic Nanomaterials for Non-invasive Disease Diagnosis

Keystroke Analytics for Non- Invasive Diagnosis of Neurodegenerative Disease

Invasive or non-invasive methods for the diagnosis of subclinical coeliac disease?

LETTERS Invasive or non-invasive methods for the diagnosis of subclinical coeliac disease? I read with great interest the letters published in Gut on the role of small bowel biopsies and antiendomysial antibodies (EMA) as methods for diagnosing coeliac disease in patients with iron deficiency anaemia (IDA) (Gut 2001;49:595). In particular, Pearce et al seem to prefer EMA instead of histological...

Invasive or non-invasive prenatal genetic diagnosis?

About 40 years ago, invasive prenatal diagnosis techniques were introduced in obstetrics. Initially, amniocentesis was performed followed by placentacentesis, fetoscopy, fetal blood sampling (FBS), and chorionic villus sampling (CVS). These procedures, while invading the uterine environment, have made it possible to proceed with the retrieval of biological tissue of fetal origin for analysis an...

Simple non-invasive biomarkers of advanced fibrosis in the evaluation of non-alcoholic fatty liver disease

BACKGROUND AND AIMS Non-alcoholic fatty liver disease (NAFLD) is a common, morbid disease with profound implications for the overall health of the patient. We set out to determine the clinical predictors of advanced histology in the referral population. METHODS We performed a retrospective review of all biopsy-proven NAFLD patients, including 358 unique patients first seen between 1996 and 20...

Clinical Manifestations and Diagnosis of Non-Alcoholic Fatty Liver Disease

Background & Objective: Nonalcoholic fatty liver diseases (NAFLD) is the major cause of hepatocellular carcinoma and increases the risk of mortality. Understanding the trends of its clinical and biochemical changes is essential to identify patients with NAFLD that are at the greatest risk of nonalcoholic steatohepatitis (NASH) and cirrhosis in Iran. M...